All-Inclusive Digestive Enzymes

All-Inclusive Digestive Enzymes

– by enabling the digestive process through the addition of especially formulated Digestive Enzymes – these particular digestive enzymes are complete, they contain all the enzymes you would need (many on the market, only contain 2 or 3 of the digestive enzymes we need) – which plays an important role in the class of IBD related diseases.

Do you suffer suffer from any of the following symptoms:

  • Indigestion?
  • Prolonged feeling of fullness ?
  • Bloating?
  • Gas?
  • Abdominal cramps?
  • Difficulty gaining weight, or losing weight?
  • Constipation (often related to roughage and fiber)?
  • Diarrhea?
  • Undigested food in the stool?

If you’ve answered yes to any of the above, then you may be suffering from weakened digestion. Continued weakend digestion may lead to:

  • malabsorption of nutrients (which could make you malnourished),
  • food allergies, intolerances and sensitivities,
  • intestinal fermentation,
  • intestinal putrefaction,
  • and intestinal hyperpermeability also known as “Leaky Gut”

It’s no secret that as we age it becomes harder to enjoy a meal without suffering from some type of digestive discomfort. The reason is that every 10 years of life the pancreas produces fewer digestive enzymes. In addition, our modern diets are largely void of natural plant enzymes. This overall lack of enzymes causes the body to work harder, putting a strain on our internal organs and digestive system. This results in symptoms as minor as heartburn and bloating, but can lead to symptoms as major as Irritable Bowel Syndrome.

Food enzymes are released by the action of chewing, which ruptures the food’s cell membranes. Like salivary enzymes, raw food enzymes play an important role in human digestion by predigesting food in the upper stomach, where contents may sit for as long as an hour before gastric secretions begin their action. Since enzymes are essentially destroyed at 118ºF, most forms of cooking and industrial food preparation render food devoid of enzyme activity. This places the full burden of digestion on body processes and reserves. In time, this burden can weaken or overwhelm an individual’s ability to process and absorb vital the food nutrients we need. Many health professionals believe that the prevalence of cooked and processed foods in modern society makes supplementation with digestive enzymes essential. Digestive enzymes also may be of benefit to those who experience poor digestion and absorption.

All-Inclusive Digestive Enzymes



Good health begins with proper digestion

Specialized cells in the pancreas, stomach and salivary glands produce digestive enzymes. These enzymes, along with those found in live foods, facilitate the break-down of food that results in their absorption and the eventual production of energy. When we eat a meal, producing digestive enzymes becomes a high priority for the body, requiring a lot of energy and adding stress to the pancreas. Despite this effort, digestive enzyme needs may still not meet the demands of the body, and undigested food particles may remain. These particles can accumulate and prevent proper nutrient absorption, cause digestive discomfort, or worse, leak back into the bloodstream from the colon and cause toxicity.

There are a many causes of indigestion and other digestive disorders. At least 10% of the population is lactose intolerant. Combine this with non-digestible complex sugars from legumes, cruciferous vegetables and cereal grains, abdominal discomfort, bloating and gas are inevitable. Others consume far more protein than their body’s enzymes can digest, resulting in digestive discomfort. Typically, people reach for an antacid, which only neutralizes stomach acid and slows the digestive process. Yet, the true cause for indigestion has not been addressed. Digestive enzyme supplementation can enhance nutrient absorption, relieve digestive discomfort and promote overall better health.

DigeSEB-GI for Complete Digestion

DigeSEB®-GI is a premium, all-inclusive blend of digestive enzymes formulated to optimize digestion of:

  • dairy,
  • legumes,
  • cruciferous vegetables,
  • cereal grains,
  • proteins,
  • and other foods

DigeSEB-GI includes:

  • alpha and beta amylase,
  • invertase, maltase,
  • alpha galactosidase,
  • lipase,
  • cellulase and
  • a complete array of protease enzymes,

all of which together, are designed to enhance the digestion of carbohydrates, proteins and fats, while increasing the nutritional value of food and reducing the discomforts of incomplete digestion.

DigeSEB-GI contains all-natural digestive enzymes specifically tailored to break down a broad range of foods into nutrients that your body can readily use. The powerful combination of proteases in DigeSEB–GI helps hydrolyze proteins into smaller peptides and amino acids. Further, these enzymes are designed to be effective across a wide pH range throughout the entire digestive track.

After about the age of two years, the body begins to produce less lactase. Undigested lactose molecules pass into the colon and are fermented by bacteria, contributing to bloating, cramping and gas. DigeSEB-GI supports the digestion of lactose, as well as casein and other proteins and fats inherent in dairy products.

DigeSEB-GI is also formulated to assist in the breakdown of carbohydrates found in vegetables, grains and legumes. Complex carbohydrates found in these foods are very nutrient dense but slow to digest. Undigested food is fermented in the colon, which can cause discomfort and limit the amount of nutrients made available for the body to absorb. The inclusion of two kinds of amylase in DigeSEB-GI helps breakdown carbohydrates and assimilates them into usable sugars and starches. The complete digestion formula also contains HemiSEB®, a special enzyme complex that breaks down hard-to-digest components of plant fiber. Alpha-galactosidase breaks down complex carbohydrates found in legumes, vegetables, and grains, while reducing the discomforts of incomplete digestion.*


Complete Digestion

  • Breaks down proteins, fats, carbohydrates and dairy products
  • Relieves indigestion, gas & bloating
  • Enhances nutrient absorption
  • Improves overall digestive function

90 capsules: $34.99 Now $29.99

180 capsules: $59.98 Now $52.98


Insufficient amounts of digestive enzymes can cause or worsen abnormal digestive conditions, such as maldigestion, food allergies and sensitivities, intestinal fermentation, putrefaction, and intestinal hyperpermeability (or “leaky gut”).

The use of digestive enzyme supplements to assist in the proper breakdown and assimilation of nutrients from food has been extensively studied and reviewed. Specifically, research using microbial-sourced enzymes supports their use to aid in healthy digestion.

In a study investigating lactose maldigestion resulting from a lactase insufficiency, lactase derived from Aspergillus oryzae was added directly to milk that was given to preschool children. Subjects showed an improvement of lactose digestion, which researchers directly linked to the additional enzymes.1

Supplementation of microbial lipase has been studied in a number of applications and shown to be beneficial.2,3 Lipase supplementation can reduce fecal fat content and total stool volume, and was found to be more effective at lower concentrations when compared to animal-sourced lipase.3

Protein digestion is an important consideration when assessing effectiveness of reducing allergy and leaky gut symptoms. Enzymes taken orally at meals may improve the digestion of dietary protein and, as a result, decrease the amount of antigenic protein particles leaking into circulation. Additionally, protease enzymes from Aspergillus oryzae appear to be absorbed intact following oral administration. It has been propsed that once in the bloodstream they may further breakdown and previously absorbed antigenic dietary proteins they encounter, potentially decreasing an allergic response.4,5

DigeSEB-GI is a complete and optimal digestive formula containing the following ingredients:

Enzymes How It Works
Amylase Breaks down carbohydrates, more specifically starch, into smaller dextrins and sugars; produced naturally by humans, microorganisms and plants
Proteases Hydrolyze protein such as casein, steak, gelatin, soy, fish and other plant and animal proteins into smaller chains of polypeptides (small proteins) and amino acids for easier uptake throughout the body
Lipase Breaks down fats into essential fatty acids needed for healthy tissues and cells*
Lactase Breaks down milk sugars (lactose)
Hemicellulase Breaks down carbohydrates, including fiber and other plant polysaccharides
Cellulase Breaks down carbohydrates, like fiber and other plant polysaccharides
Maltase Breaks down starch into the sugar maltose
Invertase Breaks down sucrose into the simple sugars glucose and fructose
Bromelain A collective name for the proteolytic (protein-digesting) enzymes found in the pineapple plant (Ananas comosus); known for its digestive properties. A good substitute for animal-based, digestive enzymes pepsin and trypsin due to its activity across a wide pH range
Serrapeptase (Peptizyme SP® Brand) Enzyme used by silkworms to dissolve their silken cocoons; A systemic enzyme which has been isolated, studied and used extensively for more than 50 years for its excellent fibrinolytic (fibrin-digesting), proteolytic (protein-digesting) and anti-inflammatory properties*
Papain Obtained from the latex of the fruit of the Papaya tree, papain has been used for centuries as an effective digestive aid*
Alpha-Galactosidase Breaks down complex carbohydrates commonly contained in legumes such as raffinose and stachyose
Amla Also known as Indian gooseberry (Emblica officinalis); a natural, efficacious antioxidant, and one of the richest sources of absorbable vitamin C
Papaya Powder From green papaya fruit; a natural source of papain and chymopapain, two enzymes well-known for their digestive and proteolytic (protein-digesting) properties

1. Whitney EN, et al. Understanding Nutrition 5th ed., St. Pail, MN: West Publishing Co., 1990; 144.

2. Schneider MU, et al. Pancreatic enzyme replacement therapy: comparative effects of conventional and enteric-coated microspheric pancreatin and acid-stable fungal enzyme preparations on steatorrhea in chronic pancreatitis. Hepato-gastroenterol. 1985; 32: 97-102.

3. Griffin SM, et al. Acid resistant lipase as a replacement therapy in chronic pancreatic exocrine insufficiency: a study in dogs. Gut 1989; 30: 1012-15.

4. Walker WA, et al. Antigen absorption from the small intestine and gastrointestinal disease. Ped Clinics N Amer. 1975; 22(4): 731-46.

5. Jackson PG, et al. Intestinal permeability in patients with eczema and food allergy. Lancet 1981; June 13: 1285-86.


What is digestive enzyme therapy?

Digestive enzyme therapy is the use of plant or animal-based dietary supplements to aid in digestion and promote balanced metabolism.* All of our products are of plant origin, meaning they are 100% vegetarian/vegan. Although the body is equipped with enzymes that perform digestive actions, certain conditions can affect their production and effectiveness. States of disease and aging are both factors affecting enzyme production and action.

What is a digestive proteolytic enzyme?

Proteolytic enzymes break down proteins into their building-blocks, which are called amino acids. The body requires 20 different amino acids, 8 of which are referred to as essential amino acids because they cannot be synthesized by the human body. These essential amino acids must be obtained from the food we eat. Without sufficient proteolytic enzymes, the body is unable to break down and absorb these necessary nutrients. Failure to fully digest proteins can result in undesirable symptoms such as bloating, abdominal cramping, flatulence and diarrhea.

How long should I take DigeSEB-GI before feeling results?

DigeSEB-GI should be taken 5-10 minutes prior to eating. The typical, recommended dose is 1 to 2 capsules per meal. There are several variables that may affect the required dosage, for example: Content of meal, Size of meal, Severity of intolerance, and Nutritional status.

Depending on these variables, along with one’s individual response to digestive enzyme therapy, the dose can be as high as 4-5 capsules per meal. It is advisable to experiment with dosage, considering there is no upper limit or adverse effects in exceeding your supplement needs.

What if I miss a dose?

Since digestive enzymes aid in digestion of food that is otherwise difficult to tolerate, finding yourself without them may be tricky. If you want to avoid the symptoms that can accompany indigestion, then the best advice would be to avoid the offending foods altogether. Unlike systemic enzymes, the effects of digestive enzymes can be seen quickly. Adjusting food content and finding an appropriate dosage is an important balance to achieve.

Why is it important to take DigeSEB-GI with food?

Since DigeSEB-GI aids in overall digestion, it is contraindicated to use the enzyme without eating. Although it is not harmful to take DigeSEB on an empty stomach, it is simply a waste of money. If you take digestive enzymes too soon before a meal, you risk the enzyme becoming inactive. The food and enzyme must be in the stomach together for proper results.

Are there any side effects involved with DigeSEB-GI?

Side effects with DigeSEB are rare, but not impossible. Mild cramping may occur, as the intestinal lining begins to cleanse. Other rare, but reported side effects include minor gastrointestinal disturbances, like bloating or gas. Starting off at a low dose can minimize any possible side effects. Side effects should clear with regular use, after a tolerance is established.

What does “proprietary blend” mean?

Proprietary refers to a patent, or ownership. Applying this concept to our digestive enzyme blend, it means that we alone own the rights to the specific blend of enzymes found in DigeSEB-GI, making our product different from similarly marketed digestive enzyme supplements. DigeSEB-GI encompasses an all-inclusive digestive aid product that assists in the digestion of several nutrients, not just beans and vegetables.

Can I take DigeSEB with other systemic or digestive enzymes?

Although digestive and systemic enzymes arenot contraindicated in terms of ingredients, they should not be taken at the same time. The purpose of digestive enzymes is to aid in digestion of specific foods, so taking them with food is an obvious recommendation. Because systemic enzymes require an empty stomach for maximum absorption, they must be taken separately from digestive enzymes. There are no adverse interactions between systemic and digestive enzymes, but they serve different purposes, and thus should be taken as directed for best results.

Can I open the capsule and pour it onto my food instead of swallowing the capsule?

If you find that you have trouble swallowing the capsules, pouring its contents onto food is definitely an option. You may also open the capsule into a glass of water, being sure to drink the entire glass. If you choose to take the enzymes this way, it is best to consume the entire content as soon as possible to ensure you are receiving the full benefits within your body (rather than on your plate).


Thank you AST Enzymes for providing natural products that work!” “I am glad to be able to provide quick, natural solutions to my patients, whether they are dealing with pain, digestive…”– Dr. Novak, Chicago, IL

“The AST staff has been very helpful and courteous!” “I have been using DigeSEB-GI for over a month now. It really works effectively on getting the job done of…”– N. Novak, Hickory Hills, IL

Supplement Facts

Serving Size: 1 Capsule Servings Per Container: 90

Amount Per Serving: % DV
DigeSEB® Super Proprietary\ Enzyme Blend: 300 mg * Amylase, Protease Blend (I, II and III), Lipase, Lactase, HemiSEB®, Cellulase, Maltase, Invertase, Bromelain, Peptizyme SP® (Serrapeptase), Papain and Alpha-Galactosidase in a base of Microcrystalline Cellulose
*Daily Value (DV) not established

Other ingredients: Microcrystalline cellulose and cellulose (vegetarian capsule)

Directions: Take 1 to 2 capsules with each meal, or as directed by your healthcare professional. Store in cool, dry place with the lid tightly closed. Avoid excessive heat. Keep out of the reach of children.

Caution: If you are pregnant, nursing, taking any medication or under medical supervision, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Not intended for use by persons under the age of 18.

Non GMO Free of pesticides, chemicals, preservatives, animal derivatives, dairy, lactose, yeast, fish or shellfish, peanuts, tree nuts, artificial sweeteners and colors.

Professional Strength All individual enzymes and probiotics are kosher-certified, and suitable for vegetarians and vegans.

Non GMOBioactive Protein Peptide System (BPPS®) is a proprietary manufacturing process featuring complementary bioactive peptides, ensuring greater enzyme stability, absorption and bio-availability.

Where do I buy my DigeSEB-GI Enzymes?

You can get them here

To Get Your $10.Off Coupon, any variety and any size Urthbox, Use code: SUMMERSNACKS  (through June)


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